The process of determining the whole or entire DNA sequence of an organisms at a single time is called as Whole genome sequencing. It is an comprehensive research tool for sequencing and analyzing the entire human genomes. It can detect a single nucleotide variants to find exonic regions which are poorly captured and to detect the larger genotype variants by single or clustered insertions, deletions and copy number changes. The tool is for gene sequencing at SNP level to capture functional variants from association studies. This improves knowledge for evolutionary biology and can be a therapeutic intervention for for the future of personalised medicine. It is also useful in identifiying the inherited disorders and possible diseases by the mapping of genomic information through sequencing. It also characterize the mutations that derive the progression of cancer and disease outbreak.
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